Hinges Affect Permeability: Dynamic and Permeability Studies of Triazine Containing Macrocycles

Type: Graduate
Author(s): Casey Patterson-Gardner Chemistry & Biochemistry
Advisor(s): Eric Simanek Chemistry & Biochemistry
Location: Third Floor, Table 1, Position 1, 1:45-3:45

Chameleonicity, or the ability for a molecule to change its shape to match its environment, is an often-beneficial quality of potential drug candidates, allowing for greater cell permeation. Our group has previously reported several macrocycles exhibiting dynamic hinging motion, allowing the macrocycles to adopt various conformations and giving rise to chameleonic qualities. However, the extent of hinging (e.g., the rate and barrier to hinging) were contingent on the bulk of an amino acid’s side chain. Here, five 24-membered triazine-based macrocycles are introduced with varying alkyl substituents on the hydrazone moiety of our macrocycles, distant from the hinging axis. The macrocycles are obtained by a facile three step process in high yields at each step, with the macrocyclization yielding quantitative folded and dynamic macrocycles. Using rOesy NMR, the macrocycles’ conformation and rotamer state is shown to be preserved. Variable-temperature NMR reveals that the hinging motion is mostly unaffected by the distant hydrazone substitution, further establishing the location and pathway of the hinging axis. The minimal impact of hinging via these substituents allows for varying groups to be placed away from the axis, preserving the dynamic motion but allowing for tuning of pharmaceutically relevant parameters (e.g., lipophilicity/water solubility with varying alkyl chains) or installment of bioactive moieties. Permeability studies with PAMPA show acceptable passive permeation of the alkyl hydrazone macrocycles, with permeability dependent on lipophilicity and dynamic motion. These results further indicate the ability of these macrocycles to be valid scaffolds for intracellular drug development.

Modulation of catalytic reactivity with pyridine ring substitutions of Fe-pyridinophane complexes

Type: Graduate
Author(s): Katherine Smith Chemistry & Biochemistry Jackson Bonnell Chemistry & Biochemistry David M. Freire Chemistry & Biochemistry
Advisor(s): Kayla Green Chemistry & Biochemistry
Location: Basement, Table 12, Position 1, 1:45-3:45

The inclusion of a pyridine moiety in the skeleton of tetra-aza macrocycles introduces rigidity while also introducing a handle by which the electronics and basicity of the ligand can be tuned. Metallation of these pyridinophanes has resulted in active mimics for metalloenzymes, such as superoxide dismutase mimics. However, recent work has explored their potential for industrially relevant catalytic reactions. Previous studies of iron RPyN3 complexes showed moderate success for a direct Suzuki-Miyaura C-C coupling reaction. In that work, it became clear that the substitution on the 4-position of the pyridine ring offered significant influence over the efficacy of the catalyst: the electron donating groups offer a better handle of modification of the electronic properties of the iron center, but the electron withdrawing groups increased the catalytic activity of the complex. In this presentation we introduce a second pyridine ring to the macrocycle skeleton, which includes a second position for modification, and compare the activity of this new RPy2N2 iron complex series to the previous RPyN3 series. Yields within this new series of iron complexes will be compared along with characterization of the respective complexes to understand what properties mitigate reactivity.

Rings of Power: Controlling SOD Mimic Activity with Pyridinophane Modifications

Type: Graduate
Author(s): Katherine Smith Chemistry & Biochemistry Cameron Bowers Biology Sarah Dunn Chemistry & Biochemistry David M. Freire Chemistry & Biochemistry Timothy M. Schwartz Chemistry & Biochemistry
Advisor(s): Kayla Green Chemistry & Biochemistry
Location: Basement, Table 7, Position 2, 11:30-1:30

Oxidative stress is caused by the accumulation of reactive oxygen species (ROS) in the body and is a key player in many maladies, including neurological diseases like Parkinson’s and Alzheimer’s disease. Superoxide dismutase (SOD) enzymes are capable of transforming the common ROS molecule superoxide (O2-) into less toxic species such as H2O2 or O2, thus protecting the body from harmful reactions of superoxide. Synthetic metal complexes show promise as SOD mimics and can be effective alternatives to therapeutic dosing of SOD enzyme for oxidative stress. In this work, we present a series of 12-membered tetra-aza pyridinophanes (Py2N2) and the corresponding copper complexes with substitutions on the 4-position of the pyridine ring. The SOD mimic capabilities of the Cu[Py2N2] series were explored using a UV-Visible spectrophotometric assay. Spectroscopic, potentiometric, and crystallographic methods were used to explore how the electronic nature of the 4-position substitution affects the electronics of the overall complex, and the complex’s activity as a SOD mimic. This work is an initial step toward developing these Cu[Py2N2] complexes as potential therapeutics for neurological diseases by mimicking SOD’s capabilities and protecting the body from oxidative stress.

A route to libraries of triazine macrocycles using dynamic covalent chemistry: Application to engineering logP

Type: Graduate
Author(s): Gretel Stokes Chemistry & Biochemistry Casey Patterson-Gardner Chemistry & Biochemistry
Advisor(s): Eric Simanek Chemistry & Biochemistry
Location: Second Floor, Table 1, Position 1, 11:30-1:30

The therapeutic potential of macrocycles provides a tantalizing opportunity in drug discovery. The design criteria, such as solubility properties, for macrocycles is only beginning to be understood. One of the significant limitations to such investigations is the synthetic challenge that macrocycles provide and the need for comparison across similar molecules. This study describes the creation of a library of macrocycles to probe and ultimately to engineer partition coefficients. Recently, the quantitative dimerization of monomers to yield 24-atom macrocycles has been described. Historically, a trichlorotriazine is substituted with BOC-hydrazine, an amino acid, and an auxiliary amine (which has been limited until this point to morpholine or dimethylamine). Subsequently, an acetal is installed and treatment with acid results in quantitative dimerization to form macrocycles. To increase the efficiency of synthesis in this study, the acetal is installed prior to the auxiliary amine—the point of divergence. Here, five auxiliary amines were installed to give five monomers. These five monomers were combined in equimolar amounts and treated with acid to induce dimerization to yield five homodimers and ten heterodimers. The octanol:water partition coefficients of these molecules reveal a compensatory effect of substitution. That is, at pH 7, the partition coefficients of the heterodimers lie between the values of the corresponding homodimers. At this pH, the logP ranges between 1.9 and 4.3, indicating that relatively small molecular changes result in large variation in the logP of these macrocycles. The ability to engineer one property—the partition coefficient—suggests that a secondary property—shape—is conserved, a hypothesis borne out by NMR spectroscopy.

Constructing a database of asphaltenes: Quantum chemistry used to contextualize single-molecule experiments within the ensemble properties of asphaltenes in crude oil

Type: Graduate
Author(s): Gretel Stokes Chemistry & Biochemistry Sydney Mazat Chemistry & Biochemistry
Advisor(s): Benjamin Janesko Chemistry & Biochemistry
Location: Third Floor, Table 8, Position 2, 1:45-3:45

Asphaltenes constitute the heaviest, most diverse, and most chemically unresolved component of petroleum crude oils. Asphaltene mixtures are structurally complex, containing thousands of distinct species with a broad range of molecular weights, functional groups, and aromaticity. The structural diversity of asphaltenes, along with their tendency to aggregate, has hindered a complete understanding of the asphaltene component of crude oil. Modern asphaltene studies have deciphered hundreds of individual asphaltene structures through atomic force microscopy (AFM). The structural diversity and expanding chemical knowledge of asphaltene structures necessitates a way to store and easily retrieve and analyze this information. Additionally, much remains unknown about the connection of these imaged structures to ensemble properties of asphaltenes in crude oil. Herein, we address these two points via creation of a database of 69 published asphaltene structures. Quantum chemistry calculations are run to determine molecular properties of these individual asphaltenes and are stored on the database. These properties include molecular weight, solubility, aromaticity, dipole moment, and HOMO-LUMO gap. The database is exploited to generate graphs—such as the UV-Vis absorbance spectrum—using these computed properties to allow for a more complete chemical description of the ensemble properties of asphaltene mixtures. Our computational predictions give a more complete chemical description of previously determined individual asphaltene structures and help contextualize them with respect to their ensemble properties in crude oil.

Yield of Protein Crystallization from metastable Liquid liquid phase separation

Type: Graduate
Author(s): Shamberia Thomas Chemistry & Biochemistry Joel Dougay Chemistry & Biochemistry Aisha Fahim Chemistry & Biochemistry
Advisor(s): Onofrio Annunziata Chemistry & Biochemistry
Location: Basement, Table 14, Position 1, 1:45-3:45

Although chromatography is a reliable purification method in protein downstream processing, it has several limitations such as loading capacity, scalability and operation costs. These are important drawbacks especially for proteins generated from cell cultures with a high yield. Protein crystallization, which does not suffer these limitations, is regarded as a promising alternative to chromatography for protein purification. However, since protein crystallization is a complex not-well-understood process, protein crystals are often produced at low yield and with poor reproducibility. Thus, its implementation in protein purification protocols remain challenging. In our lab, we designed a new strategy for enhancing protein crystallization from metastable protein-rich droplets generated by liquid-liquid phase separation (LLPS). This strategy is based on the use of two additives; the first additive is needed to induce LLPS in protein aqueous solutions, while the second additive modulates the ability of protein-rich droplets to produce crystals. A protocol for determining yields of LLPS-mediated protein crystallization was also developed. This poster reports our experimental results on yield of lysozyme crystallization in the presence of NaCl (0.15 M) as an LLPS inducer and 4-(2-hydroxyethyl)-1-piperazineethanesulfonate (HEPES) as a modulator. Our results show that addition of HEPES (0.10 M) significantly boosts lysozyme crystallization yield from ≈5% (no HEPES) to 92%. The effect of temperature and incubation time on the yield of protein crystallization yield was also investigated. Our results reveals the key role of LLPS in enhancing protein crystallization.

The Effect of Urban Development-Driven Tree Removals on Land Surface Temperature in a Growing City

Type: Graduate
Author(s): Hannah Buckhalter Environmental Sciences Brendan Lavy Environmental Sciences
Advisor(s): Brendan Lavy Environmental Sciences
Location: Second Floor, Table 3, Position 2, 11:30-1:30

In the United States, instances of heat-related illnesses are increasing in urban areas. Trees help mitigate urban heat and reduce heat-related illnesses by providing cooling effects through evapotranspiration and shade. Research has found that trees cool areas by as much as 2°C. Urban development is a primary driver of urban forest loss. To preserve the urban forest, municipalities often enact tree ordinances. The city of Austin, Texas, adopted a tree preservation ordinance in 1984 to protect trees on private and public property. To remove a protected tree, property owners must apply for a tree removal permit. Austin city staff conduct a site visit and approve or deny the request. The amount of approved tree removals, however, has increased as Austin remains one of the fastest growing cities in the United States. The purpose of this research is to examine the effect of tree removals on urban heat from 2013 to 2023. We created a geographic information system to analyze the impact of over 58,000 tree removals on land surface temperature (LST) across Austin’s city limits. Our results indicate that development-related removals significantly impact the cities changing LST. The impact of these removals on LST also varies by scale with neighborhood areas experiencing the greatest heat increases due to tree loss from development. This research contributes to the growing body of literature on urban forests and microclimates, providing information to support the conservation of urban trees and healthy environments for urban residents.

Assessing populations vulnerable to the urban heat island effect in Dallas County, Texas

Type: Graduate
Author(s): Adam Buckmeier Environmental Sciences
Advisor(s): Esayas Gebremichael Geological Sciences
Location: Second Floor, Table 8, Position 1, 1:45-3:45

Urbanization disrupts local climates by replacing natural land cover with impervious surfaces. These surfaces such as concrete and asphalt retain more heat than vegetated cover, therefore, putting these areas at risk for the urban heat island effect. This is when urban areas become significantly hotter than outlying areas and exhibit high temperature anomalies, therefore, putting its residents at risk. Another contributing factor is anthropogenic emissions of greenhouse gases from industries and automobiles. The purpose of this research is to assess areas vulnerable to the urban heat island effect in Dallas County, Texas by looking at the heat severity index (The Trust for Public Lands) and land cover data (NLCD 2021). This study aims to provide insights for planning and policies that enhance resilience to urban heat island risks in Dallas County.

PERCEPTIONS OF CONSERVATION EDUCATORS ON PROGRAM EFFECTIVENESS: A MIXED METHODS STUDY

Type: Graduate
Author(s): Camden Butterworth Environmental Sciences
Advisor(s): Brendan Lavy Environmental Sciences
Location: Third Floor, Table 9, Position 1, 1:45-3:45

Environmental education is gaining popularity and recognition as a critical strategy to reduce environmental harm, biodiversity loss, and habitat degradation. Education has been identified as a top factor contributing to people’s willingness to engage in environmentally positive conservation behaviors. Non-formal learning institutions such as zoos and aquariums have the unique ability to create and engage learned in species specific education programming. Species-specific education programs can generate high public appeal and contribute to overall environmental conservation outcomes. Research on nonformal environmental education is limited, but most often reports that short-term or single experiences may not be successful in increasing knowledge or contributing to behavior changes. The purpose of this research is to assess the perceptions of educators at non-formal institutions about the success of their conservation education programs. To do this, we conducted a mixed-methods study with educators at marine conservation centers to report on their perceived strengths, weaknesses, opportunities, and threats of education programming as well as on how they define and measure their program success. Our results revealed that educators believe their short-term education programs can be impactful and report on the factors that must be considered to maximize successful program outcomes.

An Evaluation of Water and Sediment Quality in a Mine-impacted Watershed: Case Study of Elm Creek, Picher, Oklahoma

Type: Graduate
Author(s): Colin Dixon Environmental Sciences
Advisor(s): Michael Slattery Environmental Sciences
Location: Third Floor, Table 6, Position 1, 11:30-1:30

Across the U.S. there are 1335 Superfund sites that range from abandoned mines to old military bases that pose serious risk to the public if not remediated properly. The Tar Creek Superfund site, located in Picher, OK, is one example which could contaminate downstream water supplies via contaminated water and sediment due to the heavy metals, such as Cd and Pb, left behind from the mining activities. This study seeks to determine if the ongoing remediation is effective at Tar Creek which is located within the Tar Creek Superfund site, and whether contaminated sediment is migrating downstream through the watershed.

Using Socio-economic Status and Greenspace to Locate Potential Survey Sites for Bat Foraging

Type: Graduate
Author(s): Elizabeth Hargis Environmental Sciences
Advisor(s): Victoria Bennett Environmental Sciences
Location: Basement, Table 5, Position 1, 1:45-3:45

Urbanization refers to the process of converting natural habitats into human-friendly areas, consisting of concrete structures like buildings and roads that are not typically conducive to wildlife. Despite this, many animals, including bats, are able to adapt to urban landscapes and even provide crucial ecosystem services. Bats, in particular, play a vital role in controlling pests in both agricultural and urban areas. Thus, it is imperative to understand the factors that affect their foraging activity. The aim of this project is to identify potential survey sites that can provide insight into the factors that influence prey availability and abundance.

Investigating Bat Drinking Activity in Response to Variability in Water Surface Area

Type: Graduate
Author(s): Peyton Harper Environmental Sciences
Advisor(s): Victoria Bennett Environmental Sciences
Location: Basement, Table 3, Position 1, 1:45-3:45

With species facing extinction due to human-induced disturbances, conservation efforts aim to protect wildlife and ecosystems. Urban areas, despite their modifications, can provide essential ecosystem services and support biodiversity. However, ensuring wildlife presence requires understanding resource availability and accessibility. Accessibility, defined by an individual's ability to locate and utilize resources, is influenced by landscape features such as permeability and connectivity, which can impede movement. Species-specific traits, including ecology and mode of locomotion, also play significant roles in resource access. For instance, volant species like birds and bats rely on flight to forage and drink, with their ability to maneuver affecting whether they can access a water source or not. Moreover, access may not only be dependent on the size of a water source but also by clutter (i.e., vegetation, exposed rocks and litter), which can reduce the amount of surface area that is actually available. Additionally, seasonal variations in precipitation and evapotranspiration rates can alter water levels, affecting both the size of the water source and the amount of clutter (i.e., exposing more rocks and enabling more aquatic vegetation to grow). Understanding the spatial and temporal dynamics of water surface area is crucial for effective resource management aimed at making urban environments more suitable for wildlife. Thus, we investigated the influence of variation in water surface area on bat drinking activity in an urban environment. Our study focused on six water sources in Tarrant County, Texas, using drone surveillance, thermal technology, and acoustic monitoring from March to September 2023. We hypothesized that as surface area decreased during summer, bat drinking activity would decline. By addressing one potential aspect of water resource availability and accessibility, our study contributes to to more accurate assessments of urban water resource availability and the development of sustainable conservation practices for wildlife.

Assessing Urban Wildlife Water Availability: Investigating Runoff and Evaporation Dynamics in Fort Worth Ponds

Type: Graduate
Author(s): Peyton Harper Environmental Sciences
Advisor(s): Esayas Gebremichael Geological Sciences
Location: Basement, Table 3, Position 3, 11:30-1:30

Water is an essential resource for urban wildlife, but this water needs to be available and accessible. Fort Worth is an urban area that gets hot and dry during the summer months which can cause many water sources to dry up, making them unavailable for wildlife. However, some water sources in Fort Worth may be more susceptible to drying up than others. This may be affected by runoff which in turn can be a function of different variables such as soil type, impervious surface cover, vegetation cover, elevation, and more. Additionally, differences in location-specific weather may affect evaporation rates of bodies of water. This study aims: (1) to determine the variations in six different pond sites across Fort Worth, (2) to identify the factors that potentially affect runoff and evaporation, and correlate the variables with the rate of changes of the ponds to determine their significance, and (3) use this established relationship to evaluate the susceptibility of other ponds in the area to drying up during summers.

An Assessment of the Connectivity of Parks as Pollinator Habitats in Tarrant County, Texas at Multiple Spatial Scales

Type: Graduate
Author(s): Maddie Rzucidlo Environmental Sciences
Advisor(s): Brendan Lavy Environmental Sciences
Location: Basement, Table 10, Position 2, 11:30-1:30

Pollinators are essential to the functioning of terrestrial ecosystems. Approximately 87.5% of flowering plants rely on animal pollination for reproduction (Ollerton, 2017) Due to this, pollinators are vital to the production of human consumed crops and the health of ecosystems. Urbanization drives decreases in pollinator biodiversity, species richness and abundance due to loss of habitat and fragmentation (Turo et al., 2021). Urban characteristics such as densification and impervious surfaces can cause pollinator declines and loss of pollinator services (Wenzel et al., 2020).

Tarrant County has a population of 2,110,640 and encompasses 865.2 square miles in of land north central Texas (United States Census Bureau, 2020). It is also the 15th-most populated county in the United States (United States Census Bureau, 2024). Tarrant County is also located in a major pollinator migratory pathway (National Park Service, 2019). Studies show that both population density and city size impact pollinator populations (Norton et al., 2016; Sivakoff et al., 2018). Such rapid population growth has the potential to impact pollinators and their habitats. Urban green spaces such as parks can be beneficial pollinator refuges (Serret et al., 2022). Connectivity of pollinator habitats is important for species richness and abundance (Graffigna et al., 2023). Due to the rapid population growth, land use change, and densification occurring within Tarrant County and the existence of major pollinator habitats within the area, Tarrant County parks are a compelling place to conduct landscape connectivity research on pollinators. The objective of this project is to assess the connectivity of pollinator habitats in the highly urbanized Tarrant County area. This project strives to understand how urban parks as pollinator habitats connect to one another at a range of distances for pollinator travel.

Using GIS to Determine Emergency Department and Treatment Center Proximity to Opioid Hot Spots in Tarrant County

Type: Graduate
Author(s): Naomi Alanis Interdisciplinary
Advisor(s): Esayas Gebremichael Geological Sciences
Location: Basement, Table 1, Position 2, 11:30-1:30

As opioid overdose deaths in the United States (US) continue to increase, there is an emergent need to treat those with opioid use disorder (OUD). Understanding geographic variations and their impact on different population groups in the US is now more essential than ever. Significant surges in the usage and misuse of street drugs such as heroin and fentanyl, followed by a corresponding increase in opioid-related deaths, have heightened the urgency for this understanding.

Although characteristics of US counties with persistently high rates of opioid overdose mortality and low capacity to deliver OUD medications has been identified, the counties were aggregated into regions within the US and no one specific county has been targeted. Having comprehensive data on OUD prevalence rates across Tarrant County and/or Texas would be beneficial. Current research regarding spatial associations between place features, neighborhood-level social determinants of health measures, and drug overdose deaths is limited in the realm of drug use and opioid overdose fatalities. Recognizing high-risk areas and features (hot spots) could potentially enhance the quality of the emergency department response, harm reduction services, and the precision of treatment and prevention strategies.

Identifying hot spots of opioid-related emergency needs within Tarrant County may help [re]distribute existing resources efficiently, empower community and Emergency Department (ED) based physicians to advocate for their patients, and serve as a catalyst for partnerships between John Peter Smith Hospital System (JPS) and local community groups. More broadly, this analysis may demonstrate that EDs can use geospatial analysis to address the emergency and longer-term health needs of the communities they are designed to serve.

The goal of this project is to 1) identify spatial associations between place features, neighborhood-level social determinants of health measures, and opioid drug overdose deaths (i.e., high-risk/hot spot areas) and 2) compare them to access to treatment providers (i.e., emergency departments, emergency services, and harm reduction services) to identify geographic areas where the two are not well matched.

Assessing Urban Heat Island Intensity Using Landsat Data

Type: Graduate
Author(s): Daniel Ayejoto Environmental Sciences
Advisor(s): Gebremichael Esayas Geological Sciences
Location: Basement, Table 6, Position 3, 11:30-1:30

The escalating impacts of urbanization on local climate patterns, particularly the phenomenon of Urban Heat Islands (UHIs), necessitate effective monitoring and assessment strategies. This project endeavors to evaluate the Urban Heat Island intensity in Houston, Texas, employing Landsat satellite data and Geographic Information System (GIS) tools within the ArcGIS Pro platform. The study integrates multi-temporal Landsat imagery to derive land surface temperature patterns, facilitating a comprehensive analysis of UHI dynamics over time. Spatial analytics and geospatial techniques are employed to assess the correlation between land use/land cover changes and UHI intensity, offering insights into the factors influencing urban heat dynamics. The results are expected to contribute valuable insights for urban planners and policymakers, aiding in the development of strategies to mitigate the adverse effects of UHI and enhance overall urban sustainability. Additionally, the methodology established in this project can serve as a template for assessing UHI in other urban areas, fostering a broader understanding of the urban climate dynamics.

Sedimentation & Subsurface Characterization of the Lower Cretaceous Muddy Sandstone & Upper Cretaceous Mowry Shale, Powder River Basin, Wyoming

Type: Graduate
Author(s): Chase Chavez Geological Sciences
Advisor(s): Xiangyang Xie Geological Sciences
Location: Basement, Table 12, Position 2, 1:45-3:45

Foreland basins comprise some of the most prolific hydrocarbon producing reservoirs and source rocks in the North American Rocky Mountain region. One of these major producing basins is the Powder River Basin (PRB). Located in northeastern Wyoming and extending into southeastern Montana, the PRB is one of Wyoming’s largest and most active hydrocarbon producing basins. The basin comprises various Mesozoic and Paleozoic strata with productive conventional and unconventional plays. Various studies have been done on both Mesozoic and Paleozoic stratigraphy within the basin. Historically, Cretaceous stratigraphy has been well studied and documented within the basin. However, continual industry innovations in the collection, development, and processing of subsurface geological data are making possible more refined understanding of Cretaceous stratigraphy in the basin.

This study focuses on the upper Lower Cretaceous Muddy Sandstone Formation and lower Upper Cretaceous Mowry Shale intervals at basin scale, and the implications for tectonic and eustatic evolution prior to the development of the PRB. Which controlled sedimentation, infilling, and Total Organic Carbon (TOC) weight percentage distributions of the two formations. There is a general agreement that the Mowry can be divided into upper, middle, and lower sections. The middle section has been found to contain the highest TOC percentages based on prior work done with geochemical analysis. This study will update these findings with newly collected digital well data and produce higher-density regional basin coverage with type wells, while also utilizing petrophysical calculation methods to determine TOC percentages to compare with current geochemical analysis.

The Muddy being an older conventional reservoir and the Mowry a more recent unconventional play, the collection and utilization of digitized well log data from Enverus Prism with Petrel Software, in conjunction with analysis of in-house core, provides an effective approach for producing refined structure, isochore, net sand, and TOC maps for the basin. This information can then be used in generating interpretations of sedimentation history, basin infilling, and TOC distribution. In addition, published type wells with correlated Paleozoic stratigraphy from the United States Geological Survey (USGS) are being used to generate PRB subsidence curves for multiple well locations throughout the basin to compare with maps and figures produced in Petrel. To further enhance sedimentation interpretations, U-Pb detrital zircon analysis is being conducted on the Muddy Formation sandstones collected from core. This data will be compared with published detrital zircon and subsidence work done in the western neighboring Big Horn Basin and its equivalent Muddy Formation interval.

Tracking Soil Organic Carbon in an Urban Farm Near the Trinity River

Type: Graduate
Author(s): Julie Crenwelge Geological Sciences Christelle Fayad Interdisciplinary
Advisor(s): Omar Harvey Geological Sciences
Location: Second Floor, Table 5, Position 2, 11:30-1:30

Carbon is the elemental foundation for all living things on Earth. Soil carbon sequestration is a process in which carbon dioxide is removed from the atmosphere and stored in the soil. We want to examine the soil quality and the stability of carbon in an urban farm in North Texas by comparing measurements collected in October 2022 against measurements observed and collected in October 2023. Our research question is, “What is the effect of composting on the carbon quality and quantity at the farm?” The experimental points were chosen for comparison from a previous evaluation of a 1/3-acre section of a local urban farm next to the Trinity River in Fort Worth, Texas. We collected bulk soil samples at 0-15 cm and 15-30 cm depths from ten field points previously tested with an additional 3 new control points. Thermogravimetric Analysis (TGA) will be used to determine carbon quality by analyzing derivative weights change plots. The data collected suggests that within a year the experimental farm site has maintained a good quality of soil with minor acidification and compaction, as well as an increase in level and quality of carbon. The observed farm remains an appropriate site for providing food security, eliminating food waste while simultaneously sequestering carbon.

Facies Characterization of the De Grey River's Delta Plain

Type: Graduate
Author(s): Henry Henk Geological Sciences Jacinto Garza Geological Sciences Matt Kelly Geological Sciences Mackenzie Moorhead Geological Sciences Tripp Smith Geological Sciences Andrew Winch Geological Sciences
Advisor(s): John Holbrook Geological Sciences Esayas Gebremichael Geological Sciences Simon Lang Geological Sciences Victorien Paumard Geological Sciences
Location: Second Floor, Table 6, Position 1, 11:30-1:30

Fluvial Architecture and Longitudinal Variance within the Castlegate Sandstone, Book Cliffs, UT

Type: Graduate
Author(s): Brayton Keith Geological Sciences John Holbrook Geological Sciences
Advisor(s): John Holbrook Geological Sciences
Location: Basement, Table 11, Position 2, 11:30-1:30

The upper Campanian Castlegate Sandstone in the Book Cliffs of Utah is a highly amalgamated fluvial sandstone well known as a reservoir analog for oil and gas. It comprises the lower Castlegate, the formation capping Bluecastle Tongue, and the floodplain-rich middle Castlegate deposits. The Castlegate is among the most studied fluvial deposits in the world. Despite this, there has yet to be a fluvial architecture analysis completed for these deposits which consider the longitudinal variance within the Castlegate fluvial system. This project assesses the average channel depth and discharge for the lower Castlegate, allowing analysis of the relationship between channel depth and discharge and their effect on facies distribution, depositional style and fluvial architecture in the outcrops. The lower Castlegate Sandstone is a tributary fluvial system with paleocurrents oriented primarily W-NW to E-SE comprised of stacked braided fluvial sands updip, and large, higher flow straight-meandering trunk channels downdip. Distal outcrops show three distinct depositional styles with the first representing a period of highstand during which carbonaceous floodplain and small channels of 0.5-1 m in depth and maximum 4 m in width were deposited; the second represents a localized tectonic uplift with large channels of ~15 m in width and depth and lateral accretion sets scaled accordingly, and finally the capping units of small amalgamated sands composed of classic braided style channels which represent a period of lowstand.

Insights into Sediment Transport in the DeGrey River Delta: Cyclonic Influences and Bedform Persistence

Type: Graduate
Author(s): Matthew Kelly Geological Sciences
Advisor(s): Esayas Gebremichael Geological Sciences John Holbrook Geological Sciences
Location: Basement, Table 15, Position 2, 1:45-3:45

This study characterizes the sediment transport dynamics of the fluvial portion of the DeGrey River delta, a dryland tide/wave-dominated delta along the Pilbara coast of northwestern Australia. The primary focus lies in the discernment of discrete deposits resulting from annual flood events in this ephemeral river, primarily driven by cyclones and tropical depressions during the austral summer.

Methodology combines water discharge data, digital elevation models (DEM), and Sentinel-2 change detection to model flow depth and flooding extent during storm events, linking it to riverbed shear stress and the formation of discrete flood deposits. A time series of DEM datasets, consisting of a 1-m aerial survey (2021) and drone photogrammetry surveys (2022 and 2023) were used to generate differential DEMs to accurately detect yearly morphological changes within the river channel. Field surveys of selected sites indicating presence of flood deposits enabled characterization of grain size, water flow, and structural elements.

Cyclone floods in the region cause propagation of preexisting dunes, unit bars, and compound bars. These events predominantly shape lower-flow-regime structures within medium-grained sand. Unit bars exhibit down-climbing cross-stratified sets, with variations in thickness contingent on their location within the channel ranging from 0.4-1.6 meters. Lower-flow-regime bar and bedform morphology persists and propagates between flows, despite the occurrence of intense flash floods, often generating discharges in excess of 100,000 ML/day. This challenges conventional expectations of channel excavation and the preservation of upper-flow-regime bedforms in the wake of such extreme events.

GEOCHEMICAL COMPARISON OF CENOMANIAN POST- BUDA MUDROCKS IN SOUTH TEXAS AND BIG BEND RANCH STATE PARK

Type: Graduate
Author(s): Payton OBrian Geological Sciences
Advisor(s): Richard Denne Geological Sciences
Location: Basement, Table 12, Position 2, 11:30-1:30

The Eagle Ford Shale (EFS) is an unconventional Cretaceous play producing crude oil and gas extending from northeast Leon County to the Mexico-American border in Southwest Texas. This Cenomanian -Turonian formation records the drowning of the Texas carbonate shelf and transgression of the Western Interior Seaway (WIS) into North America. Regional depositional patterns were affected by a series of changes in tectonic activity and eustatic sea level. The formation recorded a distinct change in oceanography during the Oceanic Anoxic Event 2 (OAE2) between the lower and upper EFS sections. The Boquillas Formation, age equivalent to the EFS, is found west of the producing region in Big Bend State and National Park. Outcrops of the EFS can be found along the Ouachita orogen and in the Big Bend region due to tilting during the Laramide orogeny and intrusive igneous activity. The largest known EFS equivalent outcrops have been found within the state park, however, no data had been collected in these locations. Evaluation of the geochemical properties and redox indicators of the depositional environment is essential to understanding the potential for hydrocarbons. The main method to acquire this data has been through the X-Ray Fluorescence Spectrometer (XRF). For this study I have utilized two handheld analyzers, the XRF along with the Laser Induced Breakdown Spectrometer (LIBS) for outcrop and core samples. Using both methods produces a more complete element suite including light elements not offered by XRF alone. Additionally, comparing LIBS data to the widely used XRF analyzer allows me to determine the practical usage of LIBS in petroleum geology.

Binding Dynamics of Mono- and Di-carboxylates in a Boehmite-Bayerite Series: A Flow-Adsorption Microcalorimetry Study

Type: Graduate
Author(s): Caitlin Payblas Geological Sciences
Advisor(s): Omar Harvey Geological Sciences
Location: Third Floor, Table 6, Position 2, 1:45-3:45

It is well documented that the major sorbents in soils are organic matter, silicate clays, and metal-oxyhydroxides. In particular, interactions between organic matter and fine-grained minerals, such as aluminum oxides, have been cited as important stabilizers of the humic matter in soils, which has large implications for the storage of anthropogenic carbon and pollutants (i.e., hydrophobic organic acids) in the environment (Keil and Mayer 2014). Utilizing simple organic acids containing functional groups present in humic compounds enhances understanding of metal-hydroxide and organic acid interactions at the mineral-water interface. The energetics of these interactions largely depend on the sorbate, the physico-chemical characteristics of the sorbent, and solution conditions (e.g. pH).
Ongoing work in our lab, using flow-adsorption microcalorimetry (FAMC) to directly and systematically measure energy dynamics of sorption at the oxide-water interface indicated that structural water in the lattices of boehmite and boehmite-bayerite mixed-phased samples increased binding energetics of acetate, propionate and butyrate at pH 5. The presentation will cover energy dynamics data collected for these mono-carboxylates and their respective di-carboxylate counterparts (oxalate, malonate, and succinate) binding onto a series of synthesized boehmites and bayerites. Focus will be placed on resolving effects of carboxylate carbon chain length, the number and acidity of carboxylates, and aluminum oxide surface properties on binding dynamics.

Saltwater Intrusion Along the Texas Gulf Coast: Tracking Wetlands Distribution, Adaptation, and Migration

Type: Graduate
Author(s): Robert Wright Geological Sciences
Advisor(s): Esayas Gebremichael Geological Sciences
Location: Basement, Table 6, Position 1, 1:45-3:45

Saltwater Intrusion Along the Texas Gulf Coast: Tracking Wetlands Distribution, Adaptation, and Migration

Abstract

Climate change trends in recent decades have led to sea level rise (SLR) due to increased polar ice melting. As the sea level rises, saltwater concentrations increase inland, compelling wetland species to adapt or migrate. This added stress on wetland species hampers their ability to offer ecosystem services (ES). This study will investigate the impact of saltwater intrusion (SWI) on coastal wetland species along the Texas Gulf Coast. Supervised and unsupervised classification will be the primary methods used to accurately assess the loss, gain, or migration of different groups of wetland species over two decades. Additionally, the potential effect of wetland distribution and species changes on the ES will be investigated by analyzing the spatial extent of storm surge flooding resulting from land-falling hurricanes two decades ago versus the present.

Exploring Educational Approaches in the Assessment of Self-Reported Empathy Scores in Emergency Medicine Residents

Type: Graduate
Author(s): Naomi Alanis Interdisciplinary
Advisor(s): Hao Wang Interdisciplinary
Location: Second Floor, Table 7, Position 1, 1:45-3:45

Empathy, defined as "the process of understanding a person's subjective experience by vicariously sharing that experience while maintaining an observant stance" (Zinn, 1993, p. 306) is a skill that can be challenging for many learners in post-graduate medical education. Numerous prior studies have emphasized the importance of empathy among healthcare physicians. They have shown that physician empathy scores are not only inversely correlated with physician burnout but also directly correlated with patient satisfaction (Byrd et al., 2021). Furthermore, research indicates that there exists an inverse correlational relationship between post-graduate years and empathy levels (Wolfshohl et al., 2019).

Acknowledging the significance of empathy as a crucial skill, efforts have been made to impart it to medical professionals using diverse instructional approaches. Batt-Rawden et al. (2013) conducted a systematic review of methods employed in teaching medical students, while Patel et al. (2019) examined empathy and compassion education in medical training. However, the findings from both reviews failed to conclusively identify a single, effective instructional strategy for enhancing empathy scores among graduate medical education learners. Nonetheless, they highlighted the potential for enhancing clinicians' empathy scores through specific educational methods and pinpointed five clinical behaviors as particularly influential on individual empathy scores. Moreover, they suggested that activities should adopt a "relationship-centered" approach (Batt-Rawden et al., 2013, p. 1175). In a separate study, Hojat et al. (2013) outlined a rubric delineating the three roles of a physician and their associated performance elements.

In this prospective multi-center survey study, forty-five (45) EM residents from an ACGME-sponsored three-year Emergency Medicine (EM) residency program will complete three educational sessions using team-based learning instructional strategies on empathy. The sessions will occur monthly across three consecutive months from in the spring and summer of 2024, each lasting for one hour in length during resident didactics. Empathy scores will be obtained from all participants via the Jefferson Scale of Empathy (JSE) in a pretest-posttest manner. The pre-test questionnaire will be administered before (pre-test) the educcational sessions and after the residents have completed all of the team-based learning instructional activities (post-test).

While there has been no prior application of team-based learning to enhance empathy scores, Borges et al. (2012) employed a team-based approach to instruct third-year medical students on emotional intelligence. Given that this approach also incorporates similar "relationship-centered" tasks, we posit that team-based learning could serve as a suitable instructional strategy for improving empathy scores.

References:
1. Batt-Rawden, Samantha A. MBChB; Chisolm, Margaret S. MD; Anton, Blair; Flickinger, Tabor E. MD, MPH. Teaching Empathy to Medical Students: An Updated, Systematic Review. Academic Medicine 88(8):p 1171-1177, August 2013. | DOI:10.1097/ACM.0b013e318299f3e3
2. Boisse, A., Porath, C. “Practice Empathy as a Team.” Harvard Business Review, (February 2023): https://hbr.org/2023/02/practice-empathy-as-a-team.
3. Borges, N., Kirkham, K., Deardorff, A. & Moore, J. (2012) Development of emotional intelligence in a team-based learning internal medicine clerkship, Medical Teacher, 34:10, 802-806, DOI: 10.3109/0142159X.2012.687121
4. Byrd, J., Knowles, H., Moore, S., Acker, V., Bell, S., Alanis, N., Zhou, Y., d'Etienne, J. P., Kline, J. A., & Wang, H. (2021). Synergistic effects of emergency physician empathy and burnout on patient satisfaction: a prospective observational study. Emergency medicine journal: EMJ, 38(4), 290–296. https://doi.org/10.1136/emermed-2019-209393
5. Hardee JT. An Overview of Empathy. Perm J. 2003 Fall;7(4):51–4. PMCID: PMC5571783.
6. Hojat, M., Mangione, S., Nasca, T. J., Cohen, M. J. M., Gonnella, J. S., Erdmann, J. B., Veloski, J., & Magee, M. (2001). The Jefferson Scale of Physician Empathy: Development and Preliminary Psychometric Data. Educational and Psychological Measurement, 61(2), 349–365. https://doi.org/10.1177/00131640121971158
7. Patel, S., Pelletier-Bui, A., Smith, S., Roberts, M. B., Kilgannon, H., Trzeciak, S., & Roberts, B. W. (2019). Curricula for empathy and compassion training in medical education: A systematic review. PloS one, 14(8), e0221412. https://doi.org/10.1371/journal.pone.0221412
8. Wolfshohl, J. A., Bradley, K., Bell, C., Bell, S., Hodges, C., Knowles, H., Chaudhari, B. R., Kirby, R., Kline, J. A., & Wang, H. (2019). Association Between Empathy and Burnout Among Emergency Medicine Physicians. Journal of clinical medicine research, 11(7), 532–538. https://doi.org/10.14740/jocmr3878
9. Zinn W. The empathic physician. Arch Intern Med. 1993 Feb 8;153(3):306-12. PMID: 8427535.
10. Hojat, M., Erdmann J.B. & Gonnellak, J. (2013). Personality assessments and outcomes in medical education on the practice of medicine. AMEE Guide No. 79, Medical Teacher, 35(7), 1267-1301